See Structure-property correlations.
Structure-activity relationship (SAR)
Structure-activity relationship is the relationship between chemical structure and pharmacological activity for a series of compounds.
Structure-based design
Structure-based design is a drug design strategy based on the 3D structure of the target obtained by X-ray or NMR.
Structure-property correlations (SPC)
Structure-property correlations refers to all statistical mathematical methods used to correlate any structural property to any other property (intrinsic, chemical or biological), using statistical regression and pattern recognition techniques.
Systemic
Systemic means relating to or affecting the whole body.
Teratogen
A teratogen is a substance that produces a malformation in a foetus.
Three-dimensional Quantitative Structure-Activity Relationship (3D-QSAR)
A three-dimensional quantitative structure-activity relationship is the analysis of the quantitative relationship between the biological activity of a set of compounds and their spatial properties using statistical methods.
Topliss tree
A Topliss tree is an operational scheme for analog design.
Transition-state analog
A transition-state analog is a compound that mimics the transition state of a substrate bound to an enzyme.
Xenobiotic
A xenobiotic is a compound foreign to an organism (xenos [greek] = foreign).
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